Guidelines for the clinical diagnosis and treatment of retinoblastoma (2025)

ABSTRACT

Retinoblastoma (RB) is the most common intraocular malignant tumor in children under five , which compromises the visual function and life of children. Since most RB patients have reached the extraocular stage at the time of initial diagnosis, the mortality rate remains high, which brings great challenges to clinical treatment. Therefore, early diagnosis and standardized treatment are of great significance for RB. To this end, the Ophthalmology Committee of the Ophthalmology Branch of the Chinese Medical Doctor Association, the Ophthalmology Committee of the International Intelligent Medical Association and the Ophthalmology Committee of the International Association of Translational Medicine presided over the formulation of the clinical diagnosis and treatment guidelines for retinoblastoma, which gave a detailed introduction to the etiology, diagnosis, staging and treatment of RB, aiming to help clinicians improve the diagnostic efficiency and formulate diagnosis and treatment plans for patients more quickly and effectively.